2. Signaling Pathways
  3. GPCR/G Protein
    Neuronal Signaling
  4. Cannabinoid Receptor

Cannabinoid Receptor

Cannabinoid Receptor

Cannabinoid Receptor

Related Products

PDF 1.36 MB

Cannabinoid receptors are currently classified into three groups: central (CB1), peripheral (CB2) and GPR55, all of which are G-protein-coupled. CB1 receptors are primarily located at central and peripheral nerve terminals. CB2 receptors are predominantly expressed in non-neuronal tissues, particularly immune cells, where they modulate cytokine release and cell migration. Recent reports have suggested that CB2 receptors may also be expressed in the CNS. GPR55 receptors are non-CB1/CB2 receptors that exhibit affinity for endogenous, plant and synthetic cannabinoids. Endogenous ligands for cannabinoid receptors have been discovered, including anandamide and 2-arachidonylglycerol.

Cannabinoid Receptor Isoform Specific Products:

Cannabinoid Receptor Isoform Comparison
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-170039
    (±)-8'-Hydroxy cannabichromene
    8'-Hydroxy cannabichromene is a phytocannabinoid metabolite.
    (±)-8'-Hydroxy cannabichromene
  • HY-14137R
    Rimonabant Hydrochloride (Standard)
    		Antagonist
    Rimonabant (Hydrochloride) (Standard) is the analytical standard of Rimonabant (Hydrochloride). This product is intended for research and analytical applications. Rimonabant Hydrochloride (SR 141716A Hydrochloride) is a highly potent and selective central cannabinoid receptor (CB1) antagonist with an Ki of 1.8 nM. Rimonabant Hydrochloride (SR 141716A Hydrochloride) also inhibits Mycobacterial membrane protein Large 3 (MMPL3).
    Rimonabant Hydrochloride (Standard)
  • HY-172043
    5-Fluoro PB-22 N-(2-fluoropentyl) isomer
    5-Fluoro PB-22 N-(2-fluoropentyl) isomer is a derivative of cannabinoid.
    5-Fluoro PB-22 N-(2-fluoropentyl) isomer
  • HY-W775348
    Tetrahydrocannabiphorol
    Tetrahydrocannabiphorol (THCP) is a phytocannabinoid.
    Tetrahydrocannabiphorol
  • HY-14136R
    Rimonabant (Standard)
    		Antagonist
    Rimonabant (Standard) is the analytical standard of Rimonabant. This product is intended for research and analytical applications. Rimonabant (SR141716) is a highly potent, brain penetrated and selective central cannabinoid receptor (CB1) antagonist with a Ki of 1.8 nM. Rimonabant (SR141716) also inhibits Mycobacterial membrane protein Large 3 (MMPL3).
    Rimonabant (Standard)
  • HY-W728163
    CH-PIATA
    		Inhibitor
    CH-PIATA is a synthetic cannabinoid with an acetamide linker. CH-PIATA can be detected as parent substance in blood samples. CH-PIATA has EC50 values of >71 and >176 nM for CB1 and CB2, respectively.
    CH-PIATA
  • HY-168817
    Δ9-Tetrahydrocannabiorcol
    Δ9-Tetrahydrocannabiorcol is structurally similar to known phytocannabinoids.
    Δ9-Tetrahydrocannabiorcol
  • HY-170733
    Cannabidiol monomethyl ether
    Cannabidiol monomethyl ether is a phytocannabinoid.
    Cannabidiol monomethyl ether
  • HY-168813
    Δ9-THCH
    Δ9-THCH is structurally similar to known phytocannabinoids.
    Δ9-THCH
  • HY-13505R
    AM281 (Standard)
    		Antagonist
    AM281 (Standard) is the analytical standard of AM281. This product is intended for research and analytical applications. AM281 is a selective CB1 receptor antagonist with an IC50 of 9.91 nM. AM281 inhibits CB2 receptor with an IC50 of 13000 nM.
    AM281 (Standard)
  • HY-170726
    (±)-CBCP
    (±)-CBCP ((±)-Cannabichromephorol) is structurally similar to known phytocannabinoids.
    (±)-CBCP
  • HY-W775308
    Cannabicyclolic acid
    Cannabicyclolic acid is a certified reference material categorized as a photodegradation product of the phytocannabinoid Cannabichromenic acid.
    Cannabicyclolic acid
  • HY-170700
    CHM-FUBIATA
    CHM-FUBIATA is structurally similar to known synthetic cannabinoids.
    CHM-FUBIATA
  • HY-172056
    PB-22 N-Pentanoic acid-3-carboxyindole metabolite
    PB-22 N-Pentanoic acid-3-carboxyindole metabolite is a metabolite of PB-22. PB-22 is a cannabinoid.
    PB-22 N-Pentanoic acid-3-carboxyindole metabolite
  • HY-135280
    MRL-650
    		Inhibitor
    MRL-650 (CB1 inverse agonist 1), a chemical probe, is a highly potent, orally active, and specific inverse agonist of CB1 receptor with IC50s of 7.5 nM and 4100 nM for CB1 and CB2 receptors, respectively. Anorexigenic effects.
    MRL-650
  • HY-170044
    iso-Hexahydrocannabinol
    iso-Hexahydrocannabinol is structurally similar to known phytocannabinoids.
    iso-Hexahydrocannabinol
  • HY-114826S
    Prostaglandin E2-1-glyceryl ester-d5
    		Activator
    Prostaglandin E2-1-glyceryl ester-d5 (PGE2-1-glyceyl ester-d5) is deuterium labeled Prostaglandin E2-1-glyceryl ester. Prostaglandin E2-1-glyceryl ester, a Prostaglandin Glycerol Ester, is an endocannabinoid ligand for the CB1 receptor. Prostaglandin E2-1-glyceryl ester induces rapid, transient elevation of intracellular free Ca2+.
    Prostaglandin E2-1-glyceryl ester-d<sub>5</sub>
  • HY-168819
    Δ8-iso-THC
    Δ8-iso-THC is structurally similar to known phytocannabinoids.
    Δ8-iso-THC
  • HY-103327R
    MJ15 (Standard)
    		Antagonist
    MJ15 (Standard) is the analytical standard of MJ15 (HY-103327). This product is intended for research and analytical applications. MJ15 is a potent and selective CB1 receptor antagonist with a Ki of 27.2 pM and an IC50 of 118.9 pM for rat CB1 receptors. MJ15 exhibits potency in obesity and hyperlipidemia models. MJ15 inhibits food intake and increases in body weight in diet-induced obese rats and mice.
    MJ15 (Standard)
  • HY-129304
    (±)-Cannabichromeorcin
    (±)-Cannabichromeorcin is a cannabinoid.
    (±)-Cannabichromeorcin
Cat. No. Product Name / Synonyms Application Reactivity
Cannabinoid Receptor Isoform Comparison

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately.